Proteomic analysis reveals that Polygonatum cyrtonema Hua polysaccharide ameliorates mice muscle atrophy in chemotherapy-induced cachexia

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tang, Xue-yang;Xie, Jing;Qin, You;Liu, Hao;Cheng, Fei;...

通讯作者：

Zhou, Rong-rong;Zeng, Hong-liang;Zhang, SH

作者机构：

[Zhang, Shui-han; Tang, Xue-yang] Hunan Univ Chinese Med, Inst Innovat & Appl Res Chinses Med, Changsha 410208, Peoples R China.

[Liu, Hao; Zhang, Shui-han; Chen, Lin; Qin, You; Xie, Jing; Cheng, Fei; Tang, Xue-yang] Hunan Acad Chinese Med, Inst Chinese Med Resources, Changsha 410013, Peoples R China.

[He, Dan; Huang, Ao; Zhang, Hai-chao] Hunan Univ Chinese Med, Hunan Acad Chinese Med, Changsha 410016, Peoples R China.

[Li, Jia-yu] Changsha Hosp Tradit Chinese Med, Changsha Hosp 8, Changsha 410199, Peoples R China.

[Lao, Jia] Resgreen Grp Int Inc, Changsha 410329, Peoples R China.

通讯机构：

[Zhang, SH ; Zeng, HL; Zhou, RR] H

Hunan Acad Chinese Med, Inst Chinese Med Resources, 8 Yuehua Rd, Changsha 410013, Hunan, Peoples R China.

语种：

英文

关键词：

Chemotherapy;Muscle atrophy;Polygonatum cyrtonema Hua polysaccharide;Proteomics

期刊：

Journal of Pharmaceutical and Biomedical Analysis

ISSN：

0731-7085

年：

2023

卷：

234

页码：

115533

DOI：

10.1016/j.jpba.2023.115533

基金类别：

Excellent Youth Project of the Hunan Education Department [21B0356]; Project of Hunan Academy of Traditional Chinese Medicine [201906]; Hunan Province Administration of Traditional Chinese Medicine [C2022042, A2022005-03]; Provincial Key Project of Hunan Academy of Traditional Chinese Medicine [202101]; Precious Chinese Medicine Resources [2060302-2101-06]; Program of Transformation and Industrialization of Scientific and Technological Achievements in Hunan Province [2020SK2029]; Program of Traditional Chinese Medicine Scientific Research [A2022002, A2022005]; Hunan Province Research and Development Plan in Key Areas [2020SK2141]

机构署名：

本校为其他机构

院系归属：

第一中医临床学院

摘要：

Polygonatum cyrtonema Hua polysaccharide (PCP) is the main bioactive compound derived from the herb Polygonati Rhizoma, known for its anti-fatigue, antioxidant, immunomodulatory, and anti-inflammatory properties. However, its effectiveness on alleviating chemotherapy-induced muscle atrophy has been unclear. In this study, we utilized proteomic analysis to investigate the effects and mechanisms of PCP on gemcitabine plus cisplatin (GC) induced muscle atrophy in mice. Quality control analysis revealed that the functional PCP, rich in glucose, is ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Proteomic analysis reveals that Polygonatum cyrtonema Hua polysaccharide ameliorates mice muscle atrophy in chemotherapy-induced cachexia

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问