Effect of Ginkgo biloba extract-761 on motor functions in permanent middle cerebral artery occlusion rats

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成果类型：

期刊论文

作者：

Zeng, Gui-Rong;Zhou, Shi-da;Shao, Ya-jie;Zhang, Miao-hong;Dong, Li-Ming;...

通讯作者：

Jiang, D.-J.

作者机构：

[Lv, Jing-wei; Zeng, Gui-Rong; Dong, Li-Ming; Liu, Xin-min] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China.

[Lv, Jing-wei; Zeng, Gui-Rong; Dong, Li-Ming; Liu, Xin-min] Peking Union Med Coll, Beijing 100193, Peoples R China.

[Shao, Ya-jie; Jiang, De-jian; Liu, Xin-Min; Zeng, Gui-Rong; Zhang, Miao-hong; Zhou, Shi-da; Liu, Xin-min] Hunan Key Lab Pharmacodynam & Safety Evaluat New, Changsha 410331, Hunan, Peoples R China.

[Shao, Ya-jie; Jiang, De-jian; Liu, Xin-Min; Zeng, Gui-Rong; Zhang, Miao-hong; Zhou, Shi-da; Liu, Xin-min] Hunan Prov Res Ctr Safety Evaluat Drugs, Changsha 410331, Hunan, Peoples R China.

[Tang, Ya-hui; Zhang, Hong-xia] Hunan Univ Chinese Med, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[Liu, Xin-min] C

[Liu, Xin-min] P

[Jiang, DJ; Liu, XM] H

Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China.

Peking Union Med Coll, Beijing 100193, Peoples R China.

语种：

英文

关键词：

Gait;Ginkgo biloba 761;Rat;Rotarod

期刊：

Phytomedicine

ISSN：

0944-7113

年：

2018

卷：

页码：

94-103

DOI：

10.1016/j.phymed.2018.05.003

基金类别：

Department of Science & Technology, Hunan province, China [2015DK3010, 2016TP1026]; CAMS Initiative for Innovative Medicine, China [2016-I2M-2-006]

机构署名：

本校为其他机构

摘要：

Background: Ginkgo biloba extract (EGb-761) has been in use to treat variety of ailments including memory loss and emotional disorders usually experienced after ischemic stroke. However, data regarding its protective role in stroke associated motor dysfunction is scarce. Purpose: The present work was designed to investigate the long-term effects of EGb-761 on the motor dysfunctions associated with permanent middle cerebral artery occlusion (pMCAO) in rats. Study Design/Methods: Focal ischemic stroke was induced in male Sprague–Dawley rats by p...

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Effect of Ginkgo biloba extract-761 on motor functions in permanent middle cerebral artery occlusion rats

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