期刊论文

中文

中国现代医学杂志

1005-8982

2009

19

21

3251-3255

10.3969/j.issn.1005-8982.2009.21.014

湖南省自然科学基金资助项目（No:06JJ50049）； 国家973计划资助项目（No:2005CB523306）；

本校为第一机构

目的 探讨针刺治疗心肌缺血的神经源性机制,并观察针刺干预在缺血再灌注损伤心肌保护中的作用机制.方法 将50只大鼠随机分为5组①空白组,②假手术组,③模型组,④高频电针组,⑤低频电针组.5组均麻醉后捆绑,全程记录心电图.空白组同期捆绑对照;假手术组开胸挂线不结扎;模型组、高频电针组和低频电针组开胸结扎大鼠左冠状动脉前降支,造成心肌缺血20 min,再灌注40 min.经以上处理后颈动脉取血,采用721分光光度计测定血清缺血修饰白蛋白(IMA)和免疫组织化学法测定下丘脑β_3-肾上腺素受体(β_3-ADK).结果 模型组大鼠心肌缺血再灌注后心电图STⅡ值明显高于空白组和假手术组,也高于低频电针组和高频电针...

[Objectives]To probe the nervours original mechanism in treating myocardial ischemia by acupuncture, and observe the mechanism of action in protecting the MIRI cardiac muscle with acupuncture. [Methods]Fifty rats were randomly divided into five groups, such as blank control group, sham operated group, model group,lower frequency of electro-acupuncture group and higher frequency of electro-acupuncture group. All these five groups were bound in anesthesia and their ECG were recorded during the whole process. The blank group was bound as the contr...