【Objective】 To explore the expression of plk1 and survivin in hepatocellular carcinoma(HCC) and provide the theory evidence for clinical diagnosis and therapy.【Methods】 The expression of plk1 and survivin in 80 patients with HCC,20 patients with cirrhosis and 20 cases of healthy subjects is detected with immunohistochemical SP three-steps method.【Results】 The positive expression rate of plk1 in HCC,hepatic tissue near the carcinoma,cirrhosis and healthy subjects are 87.5%,27.5%,0%,10%,respectively.The difference between rates above has ...