【Objective】 To study the anti-inflammatory and analgesic effects and mechanisms of Longdanyaobining pellets.【Methods】 Model of xylene-induced ear edema,albumin-induced paw edema and hot-plate test were used to testify the anti-inflammatory and analgetic effects.The expression of TNF-α in serum were measured by enzyme linked immuno-sorbent(ELISA).【Results】 The xylene-induced mice ear edema and albumin-induced rat paw edema were significantly suppressed by low(0.817 g/kg),medium(1.640 g/kg) and high(3.270 g/kg) dose of Longdanyaobi...