期刊论文

中文

中国现代医学杂志

1005-8982

2013

23

9

10-12

湖南省自然科学基金项目（No:10JJ6038）；

本校为第一机构

目的观察大鼠急性软组织损伤模型骨骼肌中AQP-3的表达变化及与骨骼肌肿胀的关系。方法SD大鼠36只,随机分成两组,造模前1 d使用10%的硫化钠对每只大鼠左后肢大腿外侧区域进行脱毛处理。正常对照组:仅在左后肢大腿外侧进行脱毛处理,并标记打击范围,不予打击造模;模型组:使用软组织打击器在脱毛区标记范围内予以打击建立急性软组织损伤肿胀的模型,不给任何药物处理。造模后1 h、6 h、1 d、3 d、5d、7 d六个时相点处死动物,每组每个时相点3只,在标记的区域内肌肉组织取材,应用实时荧光定量PCR、Western blot检测AQP-3的表达水平,行相关分析。结果在3 d、5 d、7 d三个时相点,模型组的AQP-3表达水平均...

【Objective】 To observe the changes of curing-injury cataplasma on the expression of AQP-3 in skeletal muscle of rat’s model with acute injury in soft tissue and the relationship between the changes and the skeletal muscle selling.【Methods】 Totally 36 SD rats were randomly divided into two groups,and by using 10% sodium sulfide the depilating treatment was made in the thigh lateral of each left hind leg 1 day before modeling.Normal control group：The depilatory area was merely marked with striking range,not attacked for modeling.Modeling gr...