期刊论文

中文

中国现代医学杂志

1005-8982

2017

27

2

26-30

10.3969/j.issn.1005-8982.2017.02.004

本校为第一机构

目的研究盆炎丸对解脲支原体（UU）感染小鼠血清白细胞介素2（IL-2）、白细胞介素4（IL-4）表达的影响,探讨盆炎丸防治UU感染的部分免疫学机制。方法选取SPF级8周龄BALB/c雌性小鼠40只,随机分为空白组（8只）和造模组（32只）,造模组造模成功后随机分为中药组、西药组和模型组,分别予以盆炎丸、克拉霉素和等量生理盐水灌胃,14 d后取小鼠阴道分泌物行UU培养,观察小鼠血清IL-2、IL-4表达水平。结果西药组小鼠全部转阴,清除率100%,中药组小鼠UU清除率为78%。1IL-2含量:西药组IL-2值最高,其次是中药组,模型组IL-2值最低。两两比较:与空白组比较,模型组差异无统计学意义（P>0.05）,中药组和西药组差异...

Objective To observe the effect of Penyan pills on the expressions of IL-2 and IL-4 in mice infected by Ureaplasma urealytieum （UU）, and to discuss the immune mechanism of Penyan pills. Methods Forty 8-week old female BALB/c mice in SPF level were selected, and randomly divided into two groups： the blank group with 8 mice and the model-making group with 32 mice. The model-making group was subdivided into three groups randomly： the model group, the TCM group and the Western medicine group, which were perfused respectively with saline, Penyan...