期刊论文

中文

中华中医药学刊

1673-7717

2010

28

1

54-56

10.13193/j.archtcm.2010.01.56.mol.032

基金项目：国家教育部高校博士点基金项目（20050541005） 湖南省教育厅重点项目（04A039）

本校为第一机构

目的;探讨养心通脉有效成分部位方(YTⅡ)促进血管新生,治疗心肌缺血的机理.方法:运用血清药理学的方法制备含药血清,鸡胚随机分为养心通脉方(YT Ⅰ)组、养心通脉有效部位方(YTⅡ)组、bFGF组和空白血清(KX)组;72h后观察比较YTⅡ及各含药血清对各组CAM模型鸡胚存活情况、CAM标本形态、CAM血管数量的影响.结果:加药72h后,各药物组与空白血清组比较皆有统计学意义(均PYT Ⅱ组>YT Ⅰ组>KX组趋势.结论:YTⅡ与YTⅠ、bFGF-样有促血管新生作用,且YTⅡ作用与bFGF作用相当,明显优于YTⅠ.

Objective： To investigate the mechanism of the effective components recipe of YangXinTongMai Formula on the angiogenesis and improving myocardial isehemia. Methods： The chorioallantoie membrane（CAM） model was cultured and devided into YangXinTongMai Formula（ YT Ⅰ ）group and controlled group including the effective components recipe of YangXinTongMai Formula（ YT Ⅱ_ group, bFGF group and KX group, the survival rate,growth shape and vessel counts of CAM model in every group was observed after 72 hours. Results： The vessel counts in bFGF ...