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Association of per- and polyfluoroalkyl substance exposure with metabolic syndrome and its components in adults and adolescents

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成果类型:
期刊论文
作者:
Zheng, Huizhen;Yin, Ziwei;Luo, Xi;Zhou, Yingli;Zhang, Fei;...
通讯作者:
Guo, ZH
作者机构:
[Zheng, Huizhen; Yin, Ziwei; Luo, Xi; Zhou, Yingli] Hunan Univ Chinese Med, Affiliated Hosp 1, Dept Cardiol, Changsha 410007, Peoples R China.
[Zheng, Huizhen; Yin, Ziwei; Zhang, Fei; Luo, Xi; Guo, Zhihua; Zhou, Yingli] Hunan Univ Chinese Med, Coll Chinese Med, Changsha 410208, Peoples R China.
[Guo, Zhihua] Hunan Key Lab Coll Intelligent Tradit Chinese Med, Changsha 410208, Peoples R China.
通讯机构:
[Guo, ZH ] H
Hunan Univ Chinese Med, Coll Chinese Med, Changsha 410208, Peoples R China.
Hunan Key Lab Coll Intelligent Tradit Chinese Med, Changsha 410208, Peoples R China.
语种:
英文
关键词:
Per- and polyfluoroalkyl substances;Metabolic syndrome;NHANES;Metabolism;Cardiovascular risk factors;Population-based study
期刊:
Environmental Science and Pollution Research
ISSN:
0944-1344
年:
2023
卷:
30
期:
52
页码:
112943-112958
基金类别:
This research was funded by the National Natural Science Foundation of China (Grant no. 81673955), the Provincial Key Research and Development Project of Hunan (Grant no. 2022SK2012), the Provincial Natural Science Foundation Project of Hunan (Grant no. 2021JJ30495), and the Postgraduate Innovation Project of Hunan University of Chinese Medicine (Grant no. 2022CX153).
机构署名:
本校为第一且通讯机构
院系归属:
第一中医临床学院
摘要:
Per- and polyfluoroalkyl substances (PFAS) are widespread contaminants, but few studies have explored the relationship between PFAS and levels of metabolic syndrome (MetS) in the population. The available evidence of an association is also conflicting. We selected adults and adolescents with complete PFAS data from the National Health and Nutrition Examination Survey conducted between 2003 and 2018. We analyzed the association between PFAS and MetS using multivariate logistic regression models and evaluated potential nonlinear relationships with restricted cubic spline models. Additionally, we...

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