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Effects of Panax notoginseng Saponins Combined with Astragalosides on Energy Metabolism and Neurocyte Apoptosis after Cerebral Ischemia-Reperfusion in Mice

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成果类型:
会议论文
作者:
Xiao-Ping Huang;Hua Tan;Bei-Yang Chen;Chang-Qing Deng
作者机构:
Pathophysiology Laboratory,Hunan University of Chinese Medicine,Shaoshan Road No. 113,Changsha,Hunan
Department of Histology and Embryology,Hunan University of Chinese Medicine,Changsha 410208,Hunan,Ch
语种:
英文
年:
2012
页码:
119-126
会议名称:
第四届世界中西医结合大会
会议论文集名称:
第四届世界中西医结合大会论文集
会议时间:
2012-10-20
会议地点:
天津
会议赞助商:
中国中西医结合学会<&wdkj&>天津市中西医结合学会
机构署名:
本校为第一机构
院系归属:
医学院
摘要:
  The purpose of this work was to explore the effects and molecular mechanisms of Panax notoginseng saponins (PNS) combined with Astragalosides (AST) against cerebral ischemia injury through energy metabolism and neurocyte apoptosis.C56BL/6 mice were randomly divided into sham,model,small-dose combination,moderate-dose combination,large-dose combination,AST,PNS and edaravone group,treated for 4 days;then,cerebral ischemia-reperfusion injury was established.Our results showed that AST,PNS and their combinations increased the levels of ATP,ADP ...

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