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Effects of Debaryomyces hansenii treatment on intestinal mucosa microecology in mice with antibiotic-associated diarrhea.

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成果类型:
期刊论文
作者:
Zeng, Ao;Peng, Maijiao;Liu, Huizhi;Guo, Zhaohui;Xu, Jun;...
通讯作者:
Tan, Zhoujin
作者机构:
[Zeng, Ao; Guo, Zhaohui; Xu, Jun; Wang, Shengping; Liu, Huizhi] Hunan Inst Microbiol, Changsha, Hunan, Peoples R China.
[Peng, Maijiao; Zeng, Ao; Tan, Zhoujin; He, Lu] Hunan Univ Chinese Med, Changsha, Hunan, Peoples R China.
通讯机构:
[Tan, Zhoujin] H
Hunan Univ Chinese Med, Changsha, Hunan, Peoples R China.
语种:
英文
期刊:
PLoS ONE
ISSN:
1932-6203
年:
2019
卷:
14
期:
11
页码:
e0224730
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81573951]
机构署名:
本校为通讯机构
摘要:
AIM: To confirm the effects of Debaryomyces hansenii on intestinal microecology in mice with antibiotic-associated diarrhea (AAD). METHODS: This study took the mucosal microecology as the entry point and an antibiotic mixture was used to induce diarrhea in mice. D. hansenii suspension was used to treat the mice and the bacterial communities of mucosa was analyzed using high-throughput sequencing. RESULTS: The Shannon-Wiener index indicated that the sequencing depth is reasonable and reflected the majority of microbial information. The principal coordinate analysis results showed that mice in t...

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