Moist exposed burn ointment accelerates diabetes-related wound healing by promoting re-epithelialization

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成果类型：

期刊论文

作者：

Gong, Yuanxun;Jiang, Yan;Huang, Jinmei;He, Zuofen;Tang, Qianli

作者机构：

[Gong, Yuanxun; Tang, Qianli] Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Changsha, Hunan, Peoples R China.

[Gong, Yuanxun; Tang, Qianli] Youjiang Med Univ Nationalities, Affiliated Hosp, Baise, Peoples R China.

[Jiang, Yan] Youjiang Med Univ Nationalities, West Guangxi Key Lab Prevent & Treatment High Inci, Baise, Peoples R China.

[Huang, Jinmei] Guangxi Univ Chinese Med, Grad Sch, Nanning, Peoples R China.

[He, Zuofen] YouJiang Med Univ Nationalities, Grad Sch, Baise, Peoples R China.

语种：

英文

关键词：

diabetic wound healing;Re-Epithelialization;Moist exposed burn ointment;Keratinocytes;cytokeratin

期刊：

Frontiers in Medicine

ISSN：

2296-858X

年：

2023

卷：

页码：

1042015

DOI：

10.3389/fmed.2022.1042015

基金类别：

This work was supported by the National Natural Science Foundation of China (81774327, 2020ZXYJH43, and 2021KY0541) (Baike 20204725 and yy2021sk025). The funding above provides financing during the implementation of this project.

机构署名：

本校为第一机构

院系归属：

中西医结合学院

摘要：

BackgroundThe incidence of diabetes-related wounds is widespread, and the treatment is challenging. We found that Moist Exposed Burn Ointment (MEBO) promotes the healing of diabetes-related wounds, but the mechanism is not clear. MethodsThis study aimed to explore the mechanism of MEBO on diabetic wound healing, which may be related to the promotion of re-epithelialization. A full-thickness skin resection model was established in streptozotocin (STZ)-induced diabetic mice. MEBO and Kangfuxin (KFX) were applied to the wound area, and the wound healing rate was analyzed by photographing. The gra...

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Moist exposed burn ointment accelerates diabetes-related wound healing by promoting re-epithelialization

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