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The biological function of metazoan-specific subunit nuclear factor related to kappaB binding protein of INO80 complex

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成果类型:
期刊论文
作者:
Peng, Qiyao;Wan, Dan;Zhou, Rongrong;Luo, Hongyu;Wang, Junyi;...
通讯作者:
Peng, YB;Huang, XK
作者机构:
[Zeng, Yajun; Peng, Yongbo; Peng, Qiyao; Peng, YB; Wang, Junyi; Yu, Chao] Chongqing Med Univ, Coll Pharm, Chongqing Key Lab Pharmaceut Metab Res, Chongqing 400016, Peoples R China.
[Peng, Yongbo; Zhou, Rongrong; Wan, Dan; Peng, Qiyao; Zhang, Shuihan] Hunan Acad Tradit Chinese Med, Inst Chinese Med, Changsha 410208, Peoples R China.
[Peng, Yongbo; Zhou, Rongrong; Wan, Dan; Peng, Qiyao; Zhang, Shuihan] Hunan Univ Chinese Med, Changsha 410208, Peoples R China.
[Huang, XK; Huang, Xuekuan; Luo, Hongyu] Chongqing Med Univ, Coll Tradit Chinese Med, Chongqing Key Lab Tradit Chinese Med Prevent & Cu, Chongqing 410016, Peoples R China.
[Ren, Lingyan] Chongqing Univ Sci & Technol, Sch Safety Engn, Chongqing 401331, Peoples R China.
通讯机构:
[Peng, YB ; Huang, XK ] C
Chongqing Med Univ, Coll Pharm, Chongqing Key Lab Pharmaceut Metab Res, Chongqing 400016, Peoples R China.
Chongqing Med Univ, Coll Tradit Chinese Med, Chongqing Key Lab Tradit Chinese Med Prevent & Cu, Chongqing 410016, Peoples R China.
语种:
英文
关键词:
Function and structure;INO80;NFRKB
期刊:
International Journal of Biological Macromolecules
ISSN:
0141-8130
年:
2022
卷:
203
页码:
176-183
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81202896]; Key Research and Development Project of Hunan Province [2019NK2101]; Discipline Talents Program of School of Pharmacy and Innovate Start-up Project in Chongqing Medical Univer-sity [YXY2021XSZ04]; Hong Kong Scholars Program [XJ2017054]
机构署名:
本校为其他机构
院系归属:
中医学院
摘要:
The INO80 chromatin remodeling complex plays an essential role in the regulation of gene transcription, which participate in a variety of important biological processes in cells including DNA repair and DNA replication. Difference from the yeast INO80 complex, metazoan INO80 complex have the specific subunit G, which is known as nuclear factor related to kappaB binding protein (NFRKB). Recently, NFRKB has been received much attention in many aspects, such as DNA repair, cell pluripotency, telomere protection, and protein activity regulation. To dig the new function of metazoan INO80 complex, a...

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