Objective:To explore the machenism of Electroacupuncture (EA) at Neiguan points on myocardial ischemia and reperfusion injury.Methods:myocardial ischemia and reperfusion injury was caused by ligating the left ventricular branch for 40 minustes and perfusing for 1 hour in the rabbits,and the changes of nitric oxide (NO) and nitric oxide synthase (NOS) were observed after EA at Neiguan points.Results:NO and NOS were significantly increased in myocardial ischemia and reperfusion group,and there were remarkable differences between them (