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Modulating Gut Microbiota: The Mechanism of Electroacupuncture at the "Siguan" Acupoints in Alleviating Post-Stroke Depression

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成果类型:
期刊论文
作者:
Li, Zhuoyan;Li, Lianqiu;Xu, Hui;Kang, Zhen;Shi, Xuehui;...
通讯作者:
Zhang, Peng;Ye, HM
作者机构:
[Zhang, Peng; Ye, Haimin; Zhang, P; Li, Zhuoyan; Li, Lianqiu; Xu, Hui; Kang, Zhen; Shi, Xuehui] Hunan Univ Chinese Med, Affiliated Hosp 2, Changsha 41005, Peoples R China.
[Li, Zhuoyan] Hunan Univ Chinese Med, Clin Coll Tradit Chinese Med 2, Changsha 410208, Peoples R China.
通讯机构:
[Ye, HM ; Zhang, P] H
Hunan Univ Chinese Med, Affiliated Hosp 2, Changsha 41005, Peoples R China.
语种:
英文
关键词:
post-stroke depression;acupuncture;electroacupuncture;siguan acupoints;gut microbiota
期刊:
NEUROPSYCHIATRIC DISEASE AND TREATMENT
ISSN:
1178-2021
年:
2025
卷:
21
页码:
281-294
基金类别:
Hunan Provincial Natural Science Foundation General Project [2021JJ30519, 2022JJ30450]; Clinical Medical Technology Innovation Guidance Project [2021SK51304]; Scientific Research Fund of Hunan Provincial Education Department [24A0255]; Hunan University of Chinese Medicine campus-level project [2024CX131]
机构署名:
本校为第一且通讯机构
院系归属:
第二中医临床医学院
摘要:
PURPOSE: To explore the related mechanisms of electroacupuncture at the "Siguan" acupoints in treating post-stroke depression (PSD). METHODS: Fifty male SD rats were randomly divided into the blank group, stroke group, PSD group, Siguan group and Bifidobacterium group, with 10 rats in each group. The Siguan group was given electroacupuncture at the bilateral "Hegu" (LI4) and "Taichong" (LR3), using the disperse-dense wave with a frequency of 2Hz/10Hz for 30minutes each time. The changes in depressive behaviors of rats were observed according to the sucrose consumption and the scores of the ope...

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