期刊论文

The levels of complement component 3,complement component 4,high sensitivity C reactive protein, and uric acid in serum of schizophrenia

中文

中国神经精神疾病杂志

1002-0152

2017

43

9

544-548

10.3969/j.issn.1002-0152.2017.09.008

国家自然科学基金资助项目（编号：81503276,81771448） 湖南省教育厅项目（编号：15C1044） 湖南省大学生创新性课题（编号：2017-310） 湖南中医药大学大学生创新性课题（编号：2016-21）

本校为第一机构

目的探讨精神分裂症(schizophrenia,SZ)患者血清补体C3 (complement component 3,C3)、C4(complement component 4, C4)、超敏C-反应蛋白(high sensitivity C reactive protein,hs-CRP)和尿酸(uric acid, UA)的水平变化及其临床意义。方法选择144例SZ患者为SZ组,并根据4周内有无服用抗精神病药物分为治疗组(77例)和停药组(67例),另选择同期来湘雅二医院的健康体检者147例为健康对照组。采用免疫散射比浊法、胶乳增强免疫比浊法、尿酸氧化酶法分别测定各组血清补体C3、C4、hs-CRP和UA浓度,并比较分析。结果SZ组患者血清补体C3、C4水平低于对照组[(0.99±0.17) g/L vs. (1.03±0.17) g/L、(0.21 ±...

Objective To examine serum levels of complement component 3(C3), complement component 4(C4), high sensitivity C reactive protein (hs-CRP), and uric acid (UA) in schizophrenia (SZ) patients and study their clinical significance. Methods One hundred forty-four SZ patients were recruited as SZ group. According to use of antipsychotics within four weeks, patients were divided into drug group (77 cases) and non-drug group (67 cases). One hundred forty-seven healthy subjects from health checkup center in the second XiangYa hospital during the same pe...