MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Deng, Jun;Ning, Kangwen;Liu, Danhong;Wu, Dahua;Wan, Rongwen;...

通讯作者：

Ge, Jinwen

作者机构：

[Ning, Kangwen; Deng, Jun; Liu, Danhong] Hunan Univ Chinese Med, Dept Integrated Tradit Chinese & Western Med, Changsha, Hunan, Peoples R China.

[Wu, Dahua; Wan, Rongwen] Hunan Acad Chinese Med, Dept Neurol, Affiliated Hosp, Changsha, Hunan, Peoples R China.

[Ge, Jinwen] Hunan Acad Chinese Med, Dept Deanery, Changsha, Hunan, Peoples R China.

[Ge, Jinwen] Hunan Univ Chinese Med, Hunan Acad Chinese Med, Dept Deanery, Changsha 410006, Hunan, Peoples R China.

通讯机构：

[Ge, Jinwen] D

Department of Deanery, Hunan Academy of Chinese Medicine, Changsha, Hunan, P.R. China

语种：

英文

关键词：

apoptosis;BCL2L2;intracranial aneurysms;miR-140;proliferation

期刊：

NEUROREPORT

ISSN：

0959-4965

年：

2023

卷：

期：

页码：

38-45

DOI：

10.1097/WNR.0000000000001856

基金类别：

National Natural Science Foundation of China [81774174]

机构署名：

本校为其他机构

院系归属：

中西医结合学院

摘要：

To investigate the role of miR-140/BCL2L2 axis on the formation of intracranial aneurysms. The expression of miR-140 in the serum of patients with intracranial aneurysms and healthy volunteers was detected. CCK-8 assay and Annexin V-FITC/PI double staining flow cytometry were used to evaluate the effect of miR-140 knockdown on the proliferation and apoptosis of human brain vascular smooth muscle cells (HBVSMCs). Meanwhile, the relationship between miR-140 and BCL2L2 was examined. MiR-140 was found to be upregulation in intracranial aneurysm patients. MiR-140 knock-out significantly inhibited t...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问