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Sex hormones influence the intestinal microbiota composition in mice

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成果类型:
期刊论文
作者:
Wu, Yi;Peng, Xinxin;Li, Xiaoya;Li, Dandan;Tan, Zhoujin;...
作者机构:
[Li, Xiaoya; Tan, Zhoujin; Yu, Rong; Wu, Yi; Li, Dandan] Hunan Univ Chinese Med, Coll Chinese Med, Changsha, Peoples R China.
[Li, Xiaoya; Tan, Zhoujin; Yu, Rong; Wu, Yi; Li, Dandan] Hunan Key Lab Chinese Med Prescript & Syndromes Tr, Changsha, Peoples R China.
[Peng, Xinxin] Hunan Univ Chinese Med, Dept Pediat, Affiliated Hosp 1, Changsha, Peoples R China.
语种:
英文
关键词:
intestinal mucosa-associated microbiota;Intestinal luminal content microbiota;sex hormones;Sex dimorphism traits;Gender-associated diseases
期刊:
Frontiers in Microbiology
ISSN:
1664-302X
年:
2022
卷:
13
页码:
3610
基金类别:
National Natural Science Foundation of China; National Natural Science Foundation of China Regional Innovation and Development Joint Fund Key Support Project; Provincial Natural Science Foundation of Hunan; [81874460]; [U21A20411]; [2022JJ30440]
机构署名:
本校为第一机构
院系归属:
第一中医临床学院
摘要:
Sex hormone secretion difference is one of the main reasons for sexually dimorphic traits in animals, which affects the dimorphism of the intestinal microbiota; however, their interaction is still unknown. Intestinal mucosa-associated microbiota (MAM) and intestinal luminal content microbiota (LM) belong to two different habitats according to the difference in interactions between bacteria and host intestinal epithelium/nutrients. To clarify the sexually dimorphic characteristics of MAM and LM and their correlation with sex hormones, 12 specific pathogen-free (SPF) Kunming mice from the same n...

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