Objective To investigate the best effective dose of Yangxin Tongmai formula. Methods According to the L9(3^4) orthogonal design, the components of Ginsenosides, Tanshi- nonelIA, Ginsen Polysaccharide, total alkaloid and total valotile oil were studied in different dose level in order to observe the effect of each formula on the electrocardiogram J-point shift and hemorrheology markers. Results The Ginsenosides at level 3,TanshinoneIIA at level 3, Gin- sen Polysaccharide at level 3, total alkaloid and total valotile oil at level 1 could amelio...