Potential Antioxidative and Anti-Hyperuricemic Components Targeting Superoxide Dismutase and Xanthine Oxidase Explored from Polygonatum Sibiricum Red.

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成果类型：

期刊论文

作者：

Li, Jing;Wang, Zhi;Fan, Minxia;Hu, Guangwan;Guo, Mingquan

通讯作者：

Mingquan Guo<&wdkj&>Guangwan Hu

作者机构：

[Hu, Guangwan; Fan, Minxia; Guo, Mingquan; Li, Jing] Chinese Acad Sci, Key Lab Plant Germplasm Enhancement & Specialty A, Wuhan Bot Garden, Wuhan 430074, Peoples R China.

[Hu, Guangwan; Guo, Mingquan; Li, Jing] Univ Chinese Acad Sci, Coll Life Sci, Beijing 100049, Peoples R China.

[Wang, Zhi] Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Peoples R China.

[Hu, Guangwan; Fan, Minxia; Guo, Mingquan] Chinese Acad Sci, Sino Africa Joint Res Ctr, Wuhan 430074, Peoples R China.

[Hu, Guangwan; Fan, Minxia; Guo, Mingquan] Chinese Acad Sci, Innovat Acad Drug Discovery & Dev, Shanghai 201203, Peoples R China.

通讯机构：

[Mingquan Guo; Guangwan Hu] K

Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan 430074, China<&wdkj&>College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China<&wdkj&>Sino-Africa Joint Research Center, Chinese Academy of Sciences, Wuhan 430074, China<&wdkj&>Innovation Academy for Drug Discovery and Development, Chinese Academy of Sciences, Shanghai 201203, China

语种：

英文

关键词：

Polygonatum sibiricum;UF-LC-MS;antioxidative;anti-hyperuricemic;SOD;XOD

期刊：

Antioxidants

ISSN：

2076-3921

年：

2022

卷：

期：

DOI：

10.3390/antiox11091651

基金类别：

Natural Science Foundation of Hubei Province [2021CFB263]

机构署名：

本校为其他机构

院系归属：

药学院

摘要：

Abstract: Polygonatum sibiricum Red. (P. sibiricum) has been used as a traditional Chinese medicine with a wide range of pharmacology effects. However, the responsible bioactive compounds and their mechanisms of action concerning its antioxidative and anti-hyperuricemic activities remain unexplored. In this work, the antioxidant capacity of P. sibiricum was firstly evaluated with the 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2’-azinobis-(3ethylbenzthiazoline)-6-sulfonic acid (ABTS) and ferric-reducing antioxidant power (FRAP) assays, from which ...

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Potential Antioxidative and Anti-Hyperuricemic Components Targeting Superoxide Dismutase and Xanthine Oxidase Explored from Polygonatum Sibiricum Red.

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