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Effect of Electroacupuncture at Siguan Acupoints on Expression of BDNF and TrkB Proteins in the Hippocampus of Post-Stroke Depression Rats

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成果类型:
期刊论文
作者:
Kang, Zhen;Ye, Haimin;Chen, Tao;Zhang, Peng
通讯作者:
Peng Zhang
作者机构:
[Zhang, Peng; Ye, Haimin; Kang, Zhen] Hunan Univ Chinese Med, Affiliated Hosp 2, 233 Cai E North Rd, Changsha 410005, Hunan, Peoples R China.
[Chen, Tao] Hunan Univ Tradit Chinese Med, Changsha 410208, Peoples R China.
通讯机构:
[Zhang, Peng] T
The Second Affiliated Hospital of Hunan University of Chinese Medicine, No. 233 Cai E North Road, Changsha, 410005, Hunan Province, China.
语种:
英文
关键词:
Siguan acupoints;Post-stroke depression;Hippocampus;Brain-derived neurotrophic factor;Tyrosine receptor kinase B
期刊:
Journal of Molecular Neuroscience
ISSN:
0895-8696
年:
2021
卷:
71
期:
10
页码:
2165-2171
基金类别:
This study was funded by Hunan Provincial Scientific Research Program of Traditional Chinese Medicine (no. 201984).
机构署名:
本校为其他机构
院系归属:
第二中医临床医学院
摘要:
To study the effect of electroacupuncture at the Siguan acupoints on the expression of hippocampal brain-derived neurotrophic factor (BDNF) and tyrosine receptor kinase B (TrkB) in post-stroke depression (PSD) rats, in order to explore its possible mechanism Fifty specific pathogen-free (SPF)-grade adult male Sprague-Dawley (SD) rats were randomly divided into a blank group, stroke group, PSD group, Siguan acupoint group and fluoxetine group according to the random number method. PSD rats were modeled with middle cerebral artery occlusion combi...

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