期刊论文

中文

中国针灸

0255-2930

2004

24

11

785-788

国家自然科学基金项目 （编号 :3 0 17113 6）； 湖南省教育厅重点资助项目 （编号 :0 1A0 13 ）；

本校为第一机构

目的:比较针刺足三阳经对胃黏膜损伤的保护作用及对生长抑素受体基因表达的影响,探讨经脉脏腑相关的特异性.方法:乙醇灌胃造成家兔胃溃疡模型后,采用经络刺激仪进行针刺.治疗结束后用放射免疫及PC-PCR法测定胃黏膜表皮生长因子(EGF)、生长抑素(SS)及生长抑素受体(SSR1mRNA)表达.结果:模型组EGF含量较正常组明显降低;胃黏膜损伤指数、SS含量及SSR1mRNA表达则显著升高(P

Objective To compare the protective effects of acup un cture at the three-yang meridians of foot on gastric mucosal lesion, and expre ssion of somatostatin receptor gene (SSR 1mRNA) in rabbits with gastric ulcer to further explore the specificity of the correlation between meridians and viscera. Methods Rabbit gastric ulcer model was developed by intragastric perfusion of alcohol and they were needled by meridian stimulating apparatus. After treatment, epidermal growth factor (EGF), somatostatin (SS) and expression of SSR 1mRNA in gastric mucosa were determined by radioimmunoassay and PC-PCR, ...