期刊论文

Effect of Electroacupuncture in Foot-Yangming and Foot-Shaoyang Channelon Expression of Gastric Mucosal EGFR in Gastric Injury Rats

中文

世界中西医结合杂志

1673-6613

2006

1

2

103-106

10.3969/j.issn.1673-6613.2006.02.013

90209023:国家自然科学基金 2005-CB523305:国家重点基础研究发展计划（973计划）

本校为第一机构

目的:比较电针足阳明胃经(胃经)与足少阳胆经(胆经)对应激大鼠胃粘膜表皮生长因子受体(epidermal growth factor receptor,EGFR)及其基因表达的影响,探讨电针二经对胃粘膜组织保护和治疗作用不同的机制.方法:将35只大鼠随机分为空白组,预处理模型组、胃经组、胆经组,电针模型组、胃经组、胆经组,每组5只.采用水浸束缚法(WRS)造模,电针预处理组别在电针7d后造模,电针治疗组则先造模后电针7d.实验结束后取材,采用免疫组化和反转录聚合酶链式反应(reverse transcrip tion-polymerase chain reation,RT-PCR)方法检测胃粘膜EGFR及其基因(EGFRmRNA)表达,观察电针预处理对胃粘膜的保护作用,观察电针治疗...

Objective; To observe the variance of gastric mucosal EGFR/EGFRmRNA expression between electroacupuncture( EA) on the Stomach Meridian of Foot - Yangming( SMFY) and the Gallbladder Meridian of Foot - Shaoyang( GMFY) to explore the different mechanism of EA in the two meridians for protection and treatment of gastric mucosa. Methods:35 rats were randomly divided into 7 groups, 5 rats per group. Except for normal group, all rats models were induced by water restraint stress(WRS). In the EA group after established the model, EA was given for 7 - day, then the expression of EGFR and EGFRmRNA in ga...