A ratiometric fluorescence strategy based on copper nanoclusters/carbon dots for sensitive detection of doxorubicin

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成果类型：

期刊论文

作者：

Li, Feifei;Fan, Pengfei;Chen, Xinbei;Lin, Xi;Liu, Can;...

通讯作者：

Yang, Shengyuan;Xiao, FB

作者机构：

[Hu, Congcong; Yang, Shengyuan; Yang, SY; Xiao, Fubing; Fan, Pengfei; Liu, Can; Li, Feifei; Lin, Xi] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Key Lab Typ Environm Pollut & Hlth Hazards, Hengyang 421001, Hunan, Peoples R China.

[Li, Feifei] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Endocrinol, Wuhan, Peoples R China.

[Chen, Xinbei] Hunan Univ Chinese Med, Med Sch, Changsha, Peoples R China.

[Lin, Xi] Jiading Ctr Dis Control & Prevent, Shanghai, Peoples R China.

通讯机构：

[Yang, SY; Xiao, FB ] U

Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Key Lab Typ Environm Pollut & Hlth Hazards, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

carbon dots;copper nanoclusters;doxorubicin;IFE

期刊：

Luminescence

ISSN：

1522-7235

年：

2022

卷：

期：

页码：

868-875

DOI：

10.1002/bio.4230

基金类别：

Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [20B508]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2020JJ5474]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21906077, 82073604]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Sensitive detection of doxorubicin (DOX) is critical for clinical theranostics. A novel ratiometric fluorescence strategy based on the inner filter effect (IFE) has been established for the sensitive detection of DOX by designing a ratiometric fluorescence probe. In the presence of DOX, the fluorescence intensity of copper nanoclusters (CuNCs) at 485 nm decreases, and the fluorescence intensity of carbon dots at 560 nm increases. Therefore, DOX can be quantitatively detected by measuring the ratio of the fluorescence intensities at 560 and 485 ...

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A ratiometric fluorescence strategy based on copper nanoclusters/carbon dots for sensitive detection of doxorubicin

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