A complex microsatellite at chromosome 7q33 as a new prognostic marker of colorectal cancer

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Ye, Xu;Deng, Hongyu;Su, Min;Liao, Qianjin;Huang, Dan;...

通讯作者：

Xiao, Zhi-Qiang;Cao, Deliang

作者机构：

[Xiao, Zhi-Qiang; Ye, Xu] Cent S Univ, Xiangya Hosp, Res Ctr Carcinogenesis & Targeted Therapy, Changsha 410008, Hunan, Peoples R China.

[Xiao, Zhi-Qiang; Ye, Xu] Cent S Univ, Xiangya Hosp, Higher Educ Key Lab Canc Prote & Translat Med Hun, Changsha 410005, Hunan, Peoples R China.

[Liao, Qianjin; Deng, Hongyu; Su, Min; Cao, Deliang; Ye, Xu] Cent S Univ, Hunan Canc Hosp, Changsha 410013, Hunan, Peoples R China.

[Liao, Qianjin; Deng, Hongyu; Su, Min; Cao, Deliang; Ye, Xu] Cent S Univ, Affiliated Canc Hosp, Xiangya Sch Med, Changsha 410013, Hunan, Peoples R China.

[Cao, Deliang; Huang, Dan; Liao, Duan-Fang] Hunan Univ Chinese Med, Div Stem Cell Regulat & Applicat, State Key Lab Chinese Med Powder & Med Innovat Hu, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[Xiao, Zhi-Qiang; Cao, Deliang] C

[Cao, Deliang] H

Cent S Univ, Xiangya Hosp, Res Ctr Carcinogenesis & Targeted Therapy, Changsha 410008, Hunan, Peoples R China.

Cent S Univ, Xiangya Hosp, Higher Educ Key Lab Canc Prote & Translat Med Hun, Changsha 410005, Hunan, Peoples R China.

Cent S Univ, Hunan Canc Hosp, Changsha 410013, Hunan, Peoples R China.

语种：

英文

关键词：

colorectal cancer;microsatellite;polymorphisms;prognostic marker;survival

期刊：

Oncotarget

ISSN：

1949-2553

年：

2017

卷：

期：

页码：

88760-88769

DOI：

10.18632/oncotarget.21077

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81472465]; National Basic Research Program of ChinaNational Basic Research Program of China [2013CB910502]; Natural Science Foundation of Guangxi Provence [2015GXNSFEA139003]

机构署名：

本校为通讯机构

院系归属：

药学院

摘要：

Disease-specific markers are critical for early diagnosis, targeted therapy and prognostic prediction of diseases. Current study reports a complex microsatellite as a new prognostic marker of sporadic colorectal cancer. This microsatellite located at Chromosome 7q33 is composed of three tetranucleotide tandem repeats, (TTCC)(2)(TCCC)(5)(TCCT)(7), flanked by a CT-rich sequence. We analyzed polymorphisms of this microsatellite in 158 sporadic colorectal cancer, 143 matched normal adjacent tissues (NAT) and 150 health donors. Our results showed that this complex microsatellite was instable with p...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

A complex microsatellite at chromosome 7q33 as a new prognostic marker of colorectal cancer

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问