Altered Expression of Glucocorticoid Receptor and Neuron-Specific Enolase mRNA in Peripheral Blood in First-Episode Schizophrenia and Chronic Schizophrenia

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Liu, Yong;Tang, Yamei;Li, Cunyan;Tao, Huai;Yang, Xiudeng;...

通讯作者：

Wang, Xuyi

作者机构：

[Zhang, Xianghui; Liu, Yong; Wang, Xuyi] Cent South Univ, Xiangya Hosp 2, Natl Clin Res Ctr Mental Disorders, Changsha, Peoples R China.

[Zhang, Xianghui; Liu, Yong; Wang, Xuyi] Cent South Univ, Xiangya Hosp 2, Dept Psychaitry, Changsha, Peoples R China.

[Tang, Yamei] Cent South Univ, Xiangya Hosp 2, Dept Lab Med, Changsha, Peoples R China.

[Li, Cunyan] Hunan Normal Univ, Affiliated Hosp 1, Hunan Prov Peoples Hosp, Dept Lab Med, Changsha, Peoples R China.

[Tao, Huai] Hunan Univ Chinese Med, Dept Biochem & Mol Biol, Changsha, Peoples R China.

通讯机构：

[Wang, Xuyi] C

Cent South Univ, Xiangya Hosp 2, Natl Clin Res Ctr Mental Disorders, Changsha, Peoples R China.

Cent South Univ, Xiangya Hosp 2, Dept Psychaitry, Changsha, Peoples R China.

语种：

英文

关键词：

first-episode unmedicated schizophrenia (FES);chronic schizophrenia;glucocorticoid receptor;GR transcripts containing exons 1B (GR-1B);cortisol;neuron-specific enolase;mRNA

期刊：

Frontiers in Psychiatry

ISSN：

1664-0640

年：

2020

卷：

页码：

464940

DOI：

10.3389/fpsyt.2020.00760

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81571307, 81771448, 81503276]; Hunan Provincial Natural Science Foundation of ChinaNatural Science Foundation of Hunan Province [2015JJ4069, 2018JJ2580, 2018JJ3387]; Hunan Provincial Science and Technology Bureau Foundation of China [2017SK50509]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Introduction It is well-known that altered hypothalamus-pituitary-adrenal (HPA) axis process has an important role in the neurodegenerative process in schizophrenia (SZ). However, this neurodegenerative mechanism has not been clarified in SZ. Therefore, the main purpose of this study was to determine HPA axis damage in the first-episode, unmedicated schizophrenia (FES) patients and chronic schizophrenia (CSZ) patients in comparison with healthy controls (HC) by means of quantitative analysis of the peripheral blood mRNA expression of glucocorticoid receptor (GR), GR transcripts containing exon...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Altered Expression of Glucocorticoid Receptor and Neuron-Specific Enolase mRNA in Peripheral Blood in First-Episode Schizophrenia and Chronic Schizophrenia

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问