Neurological and metabolic related pathophysiologies and treatment of comorbid diabetes with depression

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成果类型：

期刊论文

作者：

Li, Sixin;Yang, Dong;Zhou, Xuhui;Chen, Lu;Liu, Lini;...

通讯作者：

Cao, H;Liu, J;Cheng, Q

作者机构：

[Liu, Lini; Cao, H; Cao, Hui; Qiu, Huiwen; Li, Sixin; Yang, Dong; Li, Xinyu; Liu, Ying; Zhou, Xuhui] Hunan Univ Chinese Med, Sch Clin Med, Dept Psychiat, Changsha, Hunan, Peoples R China.

[Liu, Lini; Cao, Hui; Qiu, Huiwen; Li, Sixin; Yang, Dong; Li, Xinyu; Liu, Ying; Zhou, Xuhui] Brain Hosp Hunan Prov, Peoples Hosp Hunan Prov 2, Dept Psychiat, Changsha, Hunan, Peoples R China.

[Chen, Lu] Hunan Univ Chinese Med, Sch Clin Med, Dept Gastroenterol, Changsha, Hunan, Peoples R China.

[Chen, Lu] Brain Hosp Hunan Prov, Peoples Hosp Hunan Prov 2, Dept Gastroenterol, Changsha, Hunan, Peoples R China.

[Lin, Ruoheng] Cent South Univ, Xiangya Hosp 2, Natl Clin Res Ctr Mental Disorders, Dept Psychiat, Changsha, Hunan, Peoples R China.

通讯机构：

[Cheng, Q ] C

[Cao, H ; Liu, J ] H

Hunan Univ Chinese Med, Sch Clin Med, Dept Psychiat, Changsha, Hunan, Peoples R China.

Hunan Univ Chinese Med, Hosp 1, Ctr Med Res & Innovat, Changsha, Hunan, Peoples R China.

Cent South Univ, Xiangya Hosp, Dept Neurosurg, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

comorbidity;depression;diabetes mellitus;pathophysiology;treatment

期刊：

CNS Neuroscience & Therapeutics

ISSN：

1755-5930

年：

2024

卷：

期：

页码：

e14497-

DOI：

10.1111/cns.14497

基金类别：

Natural Science Foundation of China [2023JJ40362, 2022JJ30451]; Changsha City Natural Science Foundation of China [kq2208103]; National Natural Science Foundation of China [82104793]; Hunan Youth Science and Technology Talent Project [2022RC1226]

机构署名：

本校为其他机构

院系归属：

第一中医临床学院

临床医学院

摘要：

AbstractBackgroundThe comorbidity between diabetes mellitus and depression was revealed, and diabetes mellitus increased the prevalence of depressive disorder, which ranked 13th in the leading causes of disability‐adjusted life‐years. Insulin resistance, which is common in diabetes mellitus, has increased the risk of depressive symptoms in both humans and animals. However, the mechanisms behind the comorbidity are multi‐factorial and complicated. There is still no causal chain to explain the comorbidity exactly. Moreover, Selective serotonin...

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Neurological and metabolic related pathophysiologies and treatment of comorbid diabetes with depression

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