Objective: To observe and discuss the effect of Zhuanggu Zhitong Prescription on castrated female osteoporosis model. Methods: Only 3 months aged 40 SD female rats,according to the weight,were randomly divided into four groups,10 in each group,normal control group,control group,model group,Zhuanggu Zhitong Prescription group. Five days after stitches of the operation,different treatments were carried out for 13 weeks. Blood and bone samples were collected for investigations on bone mineral density,estradiol( E2),thyroid hormone( T3,T4),th...