[Li, Ming; Zuo, Huilan; Li, Wei; Gao, Feng] Cent South Univ, Xiangya Hosp 3, Cell Transplantat & Gene Therapy Inst, Changsha 410013, Hunan, Peoples R China.

[Zuo, Huilan; Gao, Feng] Cent South Univ, Xiangya Hosp 3, Dept Ultrasonog, Changsha 410013, Hunan, Peoples R China.

[Li, Ming] Changsha Stomatol Hosp, Changsha 410004, Hunan, Peoples R China.

[Li, Ming] Hunan Univ Chinese Med, Sch Stomatol, Changsha 410208, Hunan, Peoples R China.

[Zhou, Li] Cent South Univ, Xiangya Hosp, Dept Pathol, Changsha, Peoples R China.

[Li, W ] C

Cent South Univ, Xiangya Hosp 3, Dept Radiol, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.

cyclin D1;messenger RNA;mitogen activated protein kinase 1;transcription factor Fra 1;xanthohumol;CCND1 protein, human;cyclin D1;flavonoid;propiophenone derivative;protein c fos;transcription factor Fra 1;xanthohumol;animal experiment;animal model;animal tissue;antineoplastic activity;Article;cancer inhibition;clinical article;controlled study;down regulation;drug mechanism;gene mutation;human;human cell;human tissue;in vitro study;in vivo study;MAPK signaling;mouse;non small cell lung cancer;nonhuman;priority journal;protein degradation;protein expression;protein expression level;protein phosphorylation;ubiquitination;animal;cell proliferation;drug effect;drug screening;gene expression regulation;genetics;MAPK signaling;non small cell lung cancer;pathology;signal transduction;tumor cell line;Animals;Carcinoma, Non-Small-Cell Lung;Cell Line, Tumor;Cell Proliferation;Cyclin D1;Flavonoids;Gene Expression Regulation, Neoplastic;Humans;MAP Kinase Signaling System;Mice;Propiophenones;Proto-Oncogene Proteins c-fos;Signal Transduction;Xenograft Model Antitumor Assays