期刊论文

中文

重庆医学

1671-8348

2020

49

3

365-369

10.3969/j.issn.1671-8348.2020.03.005

15A139:湖南省教育厅重点项目 17C1205:湖南省教育厅一般项目

本校为第一机构

目的 探讨脂多糖(LPS)对人乳腺癌MDA-MB-231细胞增殖、迁移及侵袭的影响.方法 将人乳腺癌MDA-MB-231细胞分为空白对照组和不同浓度(5、10、20、40μg/mL)LPS组,分别培养24、48、72 h取样本,CCK8法检测各组MDA-MB-231细胞增殖率,划痕实验检测各组MDA-MB-231细胞迁移率,Transwell小室实验检测各组MDA-MB-231细胞侵袭能力.结果 与空白对照组比较,LPS能促进MDA-MB-231细胞的增殖和迁移(P

Objective To observe the effects of lipopolysaccharide(LPS)on the proliferation,migration and invasion of breast cancer MDA-MB-231 cells.Methods The human breast cancer MDA-MB-231 cells were divided into the blank control group and different concentrations LPS groups(0,5,10,20,40μg/mL)and cultured for 24,48,72 h respectively.Then the samples were taken.The proliferation rate of MDA-MB-231 cells in each group was detected by using the CCK8 method.The migration rate and invasion ability of MDA-MB-231 cells in each group were detected by using th...