Guijiajiao (Colla Carapacis et Plastri, CCP) prevents male infertility via gut microbiota modulation

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Sheng, Wen;Xu, Wenjing;Ding, Jin;Lu, Baowei;Liu, Lumei;...

通讯作者：

He, QH;Zhou, Q

作者机构：

[Sheng, Wen] Hunan Univ Chinese Med, Coll Tradit Chinese Med, Changsha 410000, Peoples R China.

[Lu, Baowei; Sheng, Wen; Liu, Lumei; Ding, Jin; He, Qinghu] Hunan Univ Chinese Med, Androl Lab, Changsha 410000, Peoples R China.

[Xu, Wenjing] Hunan Univ Chinese Med, Affiliated Hosp 1, Dept Dermatol, Changsha 410000, Peoples R China.

[Ding, Jin] Guangzhou Univ Tradit Chinese Med, Affiliated Baoan Hosp Tradit Chinese Med, Clin Med Coll 7, Dept Androl, Shenzhen 518000, Peoples R China.

[Lu, Baowei; Liu, Lumei] Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Changsha 410000, Peoples R China.

通讯机构：

[Zhou, Q ; He, QH ] H

Hunan Univ Chinese Med, Androl Lab, Changsha 410000, Peoples R China.

Hunan Univ Med, Coll Tradit Chinese Med, Changsha 410000, Peoples R China.

Hunan Univ Chinese Med, Hosp 1, Dept Androl, Changsha 410000, Peoples R China.

语种：

英文

关键词：

Colla Carapacis et Plastri;Fecal microbiota transplantation;Male infertility;Gut microbiota;Spermatogenesis ability

期刊：

中国天然药物

ISSN：

2095-6975

年：

2023

卷：

期：

页码：

403-410

DOI：

10.1016/S1875-5364(23)60471-6

基金类别：

Excellent Youth Project of Scientific Research Program of Hunan Education Department(No.22B0370) Project of Traditional Chinese Medicine Administration of Hunan Province(No.B2023034) Hunan Natural Science Foundation(No.2022JJ40305).

机构署名：

本校为第一且通讯机构

院系归属：

中医学院

第一中医临床学院

中西医结合学院

摘要：

[ABSTRACT] Male infertility is a significant cause of psychosocial and marital distress in approximately 50% of couples who are unable to conceive, with male factors being the underlying cause. Guijiajiao (Colla Carapacis et Plastri, CCP) is a Traditional Chinese Medicine commonly used to treat male infertility. The present study aimed to investigate the potential mechanisms underlying the preventive effects of CCP on male infertility. An infertile male rat model was established using cyclophosphamide (CTX), and CCP was administered for both treatment and prevention. Fecal microbiota transplan...

摘要(中文)：

Male infertility is a significant cause of psychosocial and marital distress in approximately 50% of couples w...展开更多 Male infertility is a significant cause of psychosocial and marital distress in approximately 50% of couples who are unable to conceive,with male factors being the underlying cause.Guijiajiao(Colla Carapacis et Plastri,CCP)is a Traditional Chinese Medicine commonly used to treat male infertility.The present study aimed to investigate the potential mechanisms underlying the preventive effects of CCP on male infertility.An inf...

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Guijiajiao (Colla Carapacis et Plastri, CCP) prevents male infertility via gut microbiota modulation

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