期刊论文

Effect of Dihuang Yinzi protein on hippocampal slices of SDF-1 in rats

中文

陕西中医

1000-7369

2015

3

373-375

10.3969/j.issn.1000-7369.2015.03.058

陕西省科技厅资助项目（2012k19-05-04）；

本校为第一机构

目的：探讨地黄饮子对大鼠海马脑片SDF‐1蛋白的影响。方法：SD大鼠18只，用乙醚麻醉大鼠，分离海马组织，培养2周后，分为对照组（HOTC组）和低氧缺糖组（OGD组）。采用地黄饮子含药血清培养海马脑片，观察地黄饮子含药血清对海马脑片SDF‐1的影响。结果：研究发现用地黄饮子含药血清培养大鼠脑片，能明显提高缺血、缺氧组脑片SDF‐1蛋白、CXCR4含量，与对照组比较具有显著差异，说明地黄饮子能促进缺血区SDF‐1的表达，进一步促进低氧低糖区脑组织神经再生能力。结论：地黄饮子含药血清能有效提高缺血缺氧区脑片SDF‐1含量，进一步改善脑组织缺血缺氧能力，通过SDF‐1／CXCR4信号通路促进脑组...

Objective：To study Dihuang Yinzi protein in rat hippocampal slices of SDF‐1 .Methods：18 SD rats , rats with ether anesthesia ,separation of hippocampus ,training 2 weeks later ,divided into the control group （group HOTC） and low oxygen lack of sugar group （OGD group） .Using Dihuang Yinzi drug‐containing serum cultured hipp‐ocampal slices ,observation of Dihuang Yinzi drug‐containing serum affect hippocampal slices of SDF‐1 .Results ：The study found that with Dihuang Yinzi drug‐containing serum training rats ,can significantly impro...