期刊论文

中文

陕西中医

1000-7369

2020

41

2

217-219

10.3969/j.issn.1000-7369.2020.02.021

湖南省教育厅一般项目（18C0366）；

本校为第一机构

中医无动脉粥样硬化相对应病名,常归属于"胸痹"、"心痛"、"真心痛"、"中风"等范畴,其病机以痰、瘀、虚为主。现代医学研究表明,动脉粥样斑块的形成和发展过程始终伴随着炎症反应及其诱发的细胞坏死,而炎症反应与中医的痰、瘀、虚存在紧密的联系。以"虚"是炎症产生的根本,"痰瘀"是炎症激发和加剧的条件,痰瘀为标,互为因果,恶性循环的理论为指导,从痰、瘀、虚与炎症的关系,进一步探讨动脉粥样硬化的中西医病机,并结合最新研究发现,如清道夫受体内陷导致胆固醇逆转运异常、清道夫受体同时可介导低密度脂蛋白进入血管内皮、巨噬细胞转化为泡沫细胞、激活炎症通路诱发血管慢性炎症持续状态和激活细胞...

TCM has no corresponding disease name of atherosclerosis,which is often classified as"chest apoplexy","heartache","true pain"and"stroke".Its pathogenesis is mainly phlegm,blood stasis and deficiency.Modern medical studies have shown that the formation and development of atherosclerotic plaque is always accompanied by inflammatory response and cell necrosis induced by it,and inflammatory response is closely related to phlegm,blood stasis and deficiency in TCM.With "virtual"produce inflammation is fundamental,"phlegm and blood stasis"is a condition of inflammation,stimulate and aggravate,phlegm ...