Non-Coding RNA in Microglia Activation and Neuroinflammation in Alzheimer\'s Disease - 成果

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Non-Coding RNA in Microglia Activation and Neuroinflammation in Alzheimer's Disease

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

He, Chunxiang;Li, Ze;Yang, Miao;Yu, Wenjing;Luo, Rongsiqing;...

通讯作者：

Song, Zhenyan;Cheng, SW

作者机构：

[He, Chunxiang; Li, Ze; Song, Zhenyan; Cheng, Shaowu; Song, ZY; He, Jiawei; Cheng, SW; Chen, Qi; Yang, Miao; Luo, Rongsiqing; Zhou, Jinyong; Yu, Wenjing] Hunan Univ Chinese Med, Sch Integrated Chinese & Western Med, Changsha, Hunan, Peoples R China.

[He, Chunxiang; Li, Ze; Song, Zhenyan; Cheng, Shaowu; Song, ZY; He, Jiawei; Cheng, SW; Chen, Qi; Yang, Miao; Luo, Rongsiqing; Zhou, Jinyong; Yu, Wenjing] Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Key Lab Hunan Prov Integrated Tradit Chinese & Wes, Changsha, Hunan, Peoples R China.

通讯机构：

[Song, ZY; Cheng, SW ] H

Hunan Univ Chinese Med, Sch Integrated Chinese & Western Med, Changsha, Hunan, Peoples R China.

Hunan Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Key Lab Hunan Prov Integrated Tradit Chinese & Wes, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

Alzheimer’s disease;circRNA;lncRNA;miRNA;microglia activation;neuroinflammation;non-coding RNA

期刊：

Journal of Inflammation Research

ISSN：

1178-7031

年：

2023

卷：

页码：

4165-4211

DOI：

10.2147/JIR.S422114

基金类别：

National Natural Science Foundation of China [82074046, 82004184]; Hunan Provincial "Shennong Talent" Project; Natural Science Foundation of Hunan Province for Excellent Youth Project [2023JJ20033]; Science and Technology Innovation Program of Hunan Province [2023RC3166]; Postgraduate Scientific Research Innovation Project of Hunan Province [QL20220185]; Key Project for the Double First-Class Discipline of Integrating Traditional Chinese and Western Medicine in Hunan Province [2021ZXYJH12]

机构署名：

本校为第一且通讯机构

院系归属：

中西医结合学院

摘要：

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by complex pathophysiological features. Amyloid plaques resulting from extracellular amyloid deposition and neurofibrillary tangles formed by intracellular hyperphosphorylated tau accumulation serve as primary neuropathological criteria for AD diagnosis. The activation of microglia has been closely associated with these pathological manifestations. Non-coding RNA (ncRNA), a versatile molecule involved in various cellular functions such as genetic information storage and transport, as well as catalysis of biochemical reactio...

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Non-Coding RNA in Microglia Activation and Neuroinflammation in Alzheimer's Disease

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