[Qin, Yan; Wang, Wei; Xie, Qian] Hunan Univ Chinese Med, TCM & Ethnomed Innovat & Dev Int Lab, Innovat Mat Med Res Inst, Sch Pharm, Changsha 410208, Peoples R China.
通讯机构:
[Liu, B ; Wang, W ] H
Hunan Univ, Coll Biol, Hunan Prov Key Lab Plant Funct Genom & Dev Regula, Changsha 410082, Peoples R China.
Hunan Univ Chinese Med, TCM & Ethnomed Innovat & Dev Int Lab, Innovat Mat Med Res Inst, Sch Pharm, Changsha 410208, Peoples R China.
Natural Science Foundation of China [81374062, 81673179, 31672457]; Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province [2019CG03]
机构署名:
本校为通讯机构
院系归属:
药学院
摘要:
We report an intracellular imaging and assay nanoplatform for RNase A using a DNA tetrahedron-based fluorescent probe as a substrate. Importantly, a natural compound was used as an RNase A activity stimulator to improve the sensitivity. This platform provides an alternative for the diagnosis and prognosis of RNas...