期刊论文

Yu, Baosheng

英文

Open Life Sciences

2391-5412

2018

13

1

446-455

10.1515/biol-2018-0053

National Natural Science Foundation of China [81373716, 81874509, 81704182]; National Program on Key Basic Research Project of China (973 Program) [2015CB554502]; Hunan Research Project of Traditional Chinese Medicine [201518]; Planned Science and Technology Project of Hunan Province, China [2013SK3090]; Hunan Planned Science & Technology & Innovation Project (Innovation Platform and Talent) [2017RS3052]

本校为第一且通讯机构

Sini decoction (SND) is a commonly used herbal formula showing lipid-lowering effects and is applied in traditional Chinese medicine (TCM) for the treatment of cardiovascular disease (CVD) and atherosclerosis (AS). However, the mechanisms behind its anti-atherosclerotic effects are still unknown, and will be investigated in this study. AS was induced in rabbits by high fat diet (HFD) and treated with solvent (HFD group), atorvastatin (Ator group), or SND (SND group) for 12 weeks. Healthy rabbits (Chow group) were used as control. Serum and live...