期刊论文

Chen, XD

英文

Pharmacology Research & Perspectives

2052-1707

2025

13

2

e70077

10.1002/prp2.70077

This work was supported by The key research project of Hunan Provincial Administration of Traditional Chinese Medicine, C2022002; Foundation for Innovative Research Groups of the National Natural Science Foundation of China, 82374525; The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (Advantageous Disease), 201915; The Scientific Research Foundation of Hunan Provincial Department of Education, 22C0184; The Innovation Project for Graduate Students of Hunan University of Chinese Medicine, 2022CX150; Hunan Provincial Administration of Traditional Chinese Medicine, B2024048, E2022044; Hunan Provincial Clinical Medical Research Center for Ophthalmic Diseases (Traditional Chinese Medicine), 2023SK4038; The Natural Science Foundation of Hunan Province of China, 2025JJ90006; and The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (Inheritance and Innovation Project), 2024 XYLH342.

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Dry eye disease (DED) is a chronically inflammatory ocular surface disorder of unknown pathogenesis. Anti-inflammatory medications, artificial tears, autologous serum, and LipiFlow have been shown to be highly beneficial in alleviating symptoms. Nevertheless, these interventions often provide only short-term results and do not address the underlying problems of the disease. There is growing evidence that the risk of DED is associated with a vicious cycle of inflammation. This vicious cycle of inflammation is produced by the interaction of several factors, including tear film hyperosmolarity, t...