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The effect of metformin therapy on incidence and prognosis in prostate cancer: A systematic review and meta-analysis.

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成果类型:
期刊论文
作者:
He, Kancheng;Hu, Huating;Ye, Senlin;Wang, Haohui;Cui, Rongrong*;...
通讯作者:
Yi, Lu;Cui, Rongrong
作者机构:
[Yi, Lu; He, Kancheng; Wang, Haohui; Ye, Senlin] Cent S Univ, Dept Urol, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.
[Hu, Huating] Hunan Univ Chinese Med, Hosp 1, Changsha 410007, Hunan, Peoples R China.
[Cui, Rongrong] Cent S Univ, Inst Metab & Endocrinol, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.
通讯机构:
[Yi, Lu; Cui, Rongrong] C
Cent S Univ, Dept Urol, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.
Cent S Univ, Inst Metab & Endocrinol, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.
语种:
英文
期刊:
Scientific Reports
ISSN:
2045-2322
年:
2019
卷:
9
期:
1
页码:
2218
机构署名:
本校为其他机构
院系归属:
第一中医临床学院
摘要:
The relationship between metformin and prostate cancer (PCa) remains controversial. To clarify this association, the PubMed, Embase and Cochrane library databases were systematically searched from their inception dates to May 23, 2018, using the keywords "metformin" and "prostate cancer" to identify the related studies. The results included incidence, overall survival (OS), PCa-specific survival (CSS) and recurrence-free survival (RFS), which were measured as hazard ratios (HR) with a 95% confidence interval (95% CI) using Review Manager 5.3 software. A total of 30 cohort studies, including 1,...

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