A Narrative Review of Cancer-Related Fatigue (CRF) and Its Possible Pathogenesis

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成果类型：

期刊论文

作者：

Yang, Songwei;Chu, Shifeng;Gao, Yan;Ai, Qidi;Liu, Yingjiao;...

通讯作者：

Chen, Naihong

作者机构：

[Ai, Qidi; Li, Xun; Yang, Songwei; Chen, Naihong; Liu, Yingjiao; Chu, Shifeng] Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China.

[Ai, Qidi; Li, Xun; Yang, Songwei; Chen, Naihong; Liu, Yingjiao; Chu, Shifeng] Hunan Engn Technol Ctr Standardizat & Funct Chine, Changsha 410208, Hunan, Peoples R China.

[Ai, Qidi; Li, Xun; Yang, Songwei; Chen, Naihong; Gao, Yan; Liu, Yingjiao; Chu, Shifeng] Chinese Acad Med Sci, Neurosci Ctr, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China.

[Ai, Qidi; Li, Xun; Yang, Songwei; Chen, Naihong; Gao, Yan; Liu, Yingjiao; Chu, Shifeng] Peking Union Med Coll, Beijing 100050, Peoples R China.

通讯机构：

[Chen, Naihong] H

[Chen, Naihong] C

[Chen, Naihong] P

Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China.

Hunan Engn Technol Ctr Standardizat & Funct Chine, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

cancer-related fatigue;peripheral immune activation;skeletal muscle;mitochondrion;inflammatory cytokines;central nervous system

期刊：

Cells

ISSN：

2073-4409

年：

2019

卷：

期：

页码：

738

DOI：

10.3390/cells8070738

基金类别：

Hunan University of Chinese Medicine First-class Disciple Construction Project [201803]; Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces [2016TP2008]

机构署名：

本校为第一且通讯机构

院系归属：

药学院

摘要：

Many cancer patients suffer from severe fatigue when treated with chemotherapy or radiotherapy; however, the etiology and pathogenesis of this kind of fatigue remains unknown. Fatigue is associated with cancer itself, as well as adjuvant therapies and can persist for a long time. Cancer patients present a high degree of fatigue, which dramatically affects the quality of their everyday life. There are various clinical research studies and reviews that aimed to explore the mechanisms of cancer-related fatigue (CRF). However, there are certain lim...

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A Narrative Review of Cancer-Related Fatigue (CRF) and Its Possible Pathogenesis

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