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A Narrative Review of Cancer-Related Fatigue (CRF) and Its Possible Pathogenesis

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成果类型:
期刊论文
作者:
Yang, Songwei;Chu, Shifeng;Gao, Yan;Ai, Qidi;Liu, Yingjiao;...
通讯作者:
Chen, NH
作者机构:
[Ai, Qidi; Li, Xun; Yang, Songwei; Chen, Naihong; Liu, Yingjiao; Chu, Shifeng; Chen, NH] Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China.
[Ai, Qidi; Li, Xun; Yang, Songwei; Chen, Naihong; Liu, Yingjiao; Chu, Shifeng; Chen, NH] Hunan Engn Technol Ctr Standardizat & Funct Chine, Changsha 410208, Hunan, Peoples R China.
[Ai, Qidi; Li, Xun; Yang, Songwei; Chen, Naihong; Gao, Yan; Liu, Yingjiao; Chu, Shifeng; Chen, NH] Chinese Acad Med Sci, Neurosci Ctr, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China.
[Ai, Qidi; Li, Xun; Yang, Songwei; Chen, Naihong; Gao, Yan; Liu, Yingjiao; Chu, Shifeng; Chen, NH] Peking Union Med Coll, Beijing 100050, Peoples R China.
通讯机构:
[Chen, NH ] H
Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China.
Hunan Engn Technol Ctr Standardizat & Funct Chine, Changsha 410208, Hunan, Peoples R China.
Chinese Acad Med Sci, Neurosci Ctr, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China.
Peking Union Med Coll, Beijing 100050, Peoples R China.
语种:
英文
关键词:
cancer-related fatigue;peripheral immune activation;skeletal muscle;mitochondrion;inflammatory cytokines;central nervous system
期刊:
Cells
ISSN:
2073-4409
年:
2019
卷:
8
期:
7
页码:
738-
基金类别:
Conceptualization, N.C., S.Y. and S.C., Resources, S.Y., Y.G., Y.L., X.L. and N.C.; Writing-Original Draft Preparation, S.Y., Y.G. and S.C.; Writing-Review and Editing, S.Y., Y.G., Q.A. and S.C.; Project Administration, Q.A., S.Y., S.C. and N.C.; Funding acquisition, N.C., S.C. and Q.A. Financial support was from the Hunan University of Chinese Medicine First-class Disciple Construction Project (201803); the Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces (2016TP2008)
机构署名:
本校为其他机构
院系归属:
药学院
摘要:
Many cancer patients suffer from severe fatigue when treated with chemotherapy or radiotherapy; however, the etiology and pathogenesis of this kind of fatigue remains unknown. Fatigue is associated with cancer itself, as well as adjuvant therapies and can persist for a long time. Cancer patients present a high degree of fatigue, which dramatically affects the quality of their everyday life. There are various clinical research studies and reviews that aimed to explore the mechanisms of cancer-related fatigue (CRF). However, there are certain lim...

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