期刊论文

中文

湖南中医药大学学报

1674-070X

2010

30

3

14-16

10.3969/j.issn.1674-070X.2010.03.005.014.03

湖南省自然科学基金资助项目（07JJ6042）； 湖南省自然科学基金资助项目（07JJ6044）； 湖南中医药大学中医诊断重点学科资助；

本校为第一机构

目的 研究鬼箭羽对2型糖尿病大鼠胰岛β细胞形态学的影响.方法 应用高脂饲料加STZ造成2型糖尿病模型后,将大鼠随机分成模型组、鬼箭羽组、优降糖组3组,并设立空白对照组,模型组与空白对照组给予生理盐水,其余两组分别予以鬼箭羽、优降糖灌胃,干预4周后,尾静脉采血检测空腹血糖,对胰腺组织切片进行HE染色、免疫组化检测,观察大鼠胰岛β细胞变化.结果 鬼箭羽组大鼠空腹血糖明显低于模型组,其差异有统计学意义(P

Objective To research the influence of Euonymus alatus on islet β-cell in type 2 diabetic rats.Methods The models were induced with the high fat feed and STZ,and all rats were divided randomly into 4 groups： the control,Euonymus alatus,Glibenclamide and blank control groups were given different treatments respectively for 4 weeks,then,the fasting blood glucose to be detected,the pancreas tissues were stained with hematoxylin and eosin,and immunohistochemistry to observe the changes of islet β-cell.Results The fasting blood glucose in Euonymu...