Objective To investigate the cellular genetic character of population at high risk of nasopharyngeal carcinoma (PAHR -NPC). Methods Routine assays were carried out to determine the appearing rate of micronucleus from cultured peripheral blood leukocytes of PAHR - NPC, with cases suffering from these lesions like chronic nasopharyngitis and NPC and persons in healthy condition as the three controlling groups. Results The appearing rate of micronucleus was significantly increased among both groups of PAHR-NPC and NPC cases, with a tendency becoming higher further following the development of les...