Objective To investigate correlation between the expression of TLR4 and NF-κB proteins in juvenile laryngeal papilloma. Methods The expression of TLR4 and NF-κB proteins were detected ith immunohisto chemial method in 42 cases of juvenile laryngeal papilloma,Analysis of the correlation of the expression. Results The positive rates of TLR4 protein in juvenile laryngeal papilloma were 76.19% and higher than that in polyp of vocal cord (P