Acute cerebral ischemic-postischemic reperfution injury model in the gerbil was perfomed by ligaturing bilateral carotid arteries for 45 minutes followed by reperfution 45 minutes. The results showed that water and natrium contents in brain tissue markedly increased and microelement cuprum contents droped but kalium, ferrum and zine contents in brain tissue had no change. Injection peritoneal in the model with Bu Yang Huan Wu Tang(equivalent to original drug of 14g/Kg,ip) or tetramethylpyrazine (0. 032g/Kg, ip) 5 minutes before reperfusion, water and natrium contents in brain tissue marked dro...