期刊论文

THE INHIBITORY EFFECT OF YIQI JIEDU PIAN ON GENES EXPRESSION IN NASOPHARYNGEAL CARCINOMA CELL

中文

湖南中医药大学学报

1674-070X

1998

2

14-15

国家自然科学基金

本校为其他机构

利用ｍＲＮＡ差异显示技术研究益气解毒片（复方黄连）对鼻咽癌细胞基因表达的干预作用，旨在从基因选择性表达水平探讨其抗鼻咽癌的机理。结果表明，益气解毒片在体外能抑制鼻咽癌细胞基因的表达，同时诱导一些特异基因的表达，从而抑制鼻咽癌细胞的增殖。

Yiqi Jiedu pian(complex of coptic chinensis) has an antiproliferative effect on nasopharyngeal carcinoma (NPC).In order to understand the regulative mechanism of antiproliferative effect at molecular level,the differential display polymerase reaction was used to identify genes that were down-regulated and up-regulated after Yiqi Jiedu Pian treating human nasopharyngeal carcinoma cell line.As a result,most of genes were down regulated,a few of genes we...