期刊论文

STUDIES OF YIQIJIEDU TABLET IN ELIMINATING THE BLOCKING ACTION OF EBV-ANTIBODY

中文

湖南中医药大学学报

1674-070X

1999

1

3-4

10.3969/j.issn.1674-070X.1999.01.002

39770933:中国科学院项目（非规范项目） 98014:湖南省中医药局科研项目

本校为第一机构

采用MTT(二甲基噻唑二甲基四唑)法检测外周血单个核细胞(PBMC)对Raji细胞的杀伤作用和免疫酶法测EB病毒相关抗体(EBV VCA-IgA)的免疫阻抑作用,研究益气解毒片对该阻抑作用的解除效应.结果表明,益气解毒片一方面可以直接杀伤Raji细胞,另一方面有解除EBV VCA-IgA的封闭作用,使免疫细胞直接杀伤携带EB病毒基因的Raji细胞.提示益气解毒片可能解除EBV VCA-IgA的免疫封闭作用,从而阻断鼻咽癌(NPC)高危者向NPC的发展.

The killing action of normal person periphery blood monucler cell(PBMC)to Raji cell(EBV-transformed,EBV genome positive cell lines),the blocking action of EBV-antibody to the killing action of PBMC and the elimination of the Yiqijiedu Tablet were assayed with MTT.The results showed that Yiqijiedu Tablet could kill the Raji cell and eliminate the blocking action of EBV-antibody.This probably was the mechanism of Yiqijiedu Tablet in preventing th...