期刊论文

Effect of Electroacupuncture on Gastric Mucosal and ITFmRNA Expression Histology in Stress-induced Rats

中文

湖南中医药大学学报

1674-070X

2006

26

3

51-53+62

10.3969/j.issn.1674-070X.2006.03.022

国家自然科学基金重大项目（编号:9029023）； 国家973计划中医基础研究中专项（编号:2005-CB523305）；

本校为第一机构

目的 探讨电针足阳明足少阳经（穴）对应激大鼠胃黏膜组织形态学及肠三叶因子（intestinal trefoil factor，ITF）基因表达的影响。方法 将40只大鼠随机分为空白组、模型组、胃经组、胆经组。空白组不做任何处理，而模型组捆缚7d后造模。胃经组、胆经组须先捆缚及电针7d后再造模，造模采用水浸束缚10h。经相应处理后即取各组大鼠胃黏膜组织测胃黏膜组织肠三叶因子基因（ITFmRNA）表达，同时检测胃黏膜损伤指数（UI），光镜下观察胃黏膜损伤程度及组织学变化。结果 电针胃经组、胆经组与模型组的UI比较明显或极明显降低（P〈0．05或0．01）；电针胃经、胆经组较模型组ITFmRNA表达增高，胃经组较胆...

Objective To explore the effect and significance of on irritable electroacupuncture（EA） in the stomach and gallbladder channel gastric mucosal histology and intestinal trefoil factor（ITF）mRNA expression in rats. Methods Forty rats were randomly divided into following 4 groups： blank group（BG）, model group（MG）, stomach tunnel group（SG） and gallbladder tunnel group（GG）. All rats models, except BG, were made with water restraint stress（WRS）. Then the gastric mucosal tissue was to detecte the expression of ITF mRNA with RT-PCR method...