Objective To study the flocculation process with chitosan for Lujiao Buxue Granules. Methods On the basis of the one-factor investigation such as the dosage of chitosan, the concentration and pH of the extracting solution, temperature and whisking etc, the orthogo- nal design was selected to measure the effects on the chitosan dosage, the extracting solution concentration and extracting solution pH. Results The optimal flocculation process conditions were that the adding dosage of chitosan was 0.6mL /g, the concentration of meterials vs extract...