Objective To observe the clinical effect of Shugan Mingmu pill on the patients with Depression of the Liver and Insufficiency of the Kidney in dry type of Age-related macular degeneration (AMD). Methods All the 43 patienrts with AMD were randomly divided into treatment group(n=30) and control group(n=33). The changes of distant vision, Amsler, VEP and the multiple scores of manifestation in TCM were observed. Results Both groups were effective for AMD, The changes of distant vision, Amsler and the multiple scores of manifestation in TCM w...