期刊论文

Extraction of volatile oil of Rose banksiae in Jiuxiang Zhixie enteric tablets and study of inclusion process

中文

湖南中医药大学学报

1674-070X

2009

29

1

22-25

10.3969/j.issn.1674-070X.2009.01.008

湖南省教育厅重点项目（05A032）；

本校为第一机构

目的 优选九香止泻片中木香挥发油的提取及包合工艺.方法 以木香挥发油的质量为评价指标,研究木香挥发油提取量与药材用量的函数关系;以包舍物收率、油转移率、舍油率为指标,采用正交试验评价包合工艺.结果 木香药材用量与提取挥发油的量函数关系属一级动力学模型;包合适宜用研磨法,最优工艺条件为:β-环糊精与挥发油按6:1投料,加4倍量水,研磨1 h.结论 药材用量与挥发油提取量不成比例;该包合工艺可提高制剂的稳定性,为生产提供了科学的实验依据.

Objective To optimize the conditions for extraction of volatile oil of Rose banksiae in Jiuxiang Zhixie enteric tablets and inclusion process. Methods With the weight of volatile oil to evaluate the extraction as the target marker,single-element experiments were conducted to determine the optimum conditions for extracting the volatile oil. And the inclusion technology were studied by the transfer, content and recovery rate of the volatile oils in the complex with orthogonal design. Results The relationship between the quantity of costus root an...