期刊论文

中文

湖南中医药大学学报

1674-070X

2010

30

9

87-89

10.3969/j.issn.1674-070X.2010.09.025.087.03

株洲千金药业股份有限公司资助项目；

本校为第一机构

目的 探讨妇科千金片治疗急性盆腔炎的机制.方法 选用8周龄雌性Wistar大鼠,随机分为空白组、假手术组、模型组、妇科千金片低、中、高剂量组、妇炎康组、罗红霉素组,其中造模采用子宫内接种混合茵液制作急性盆腔炎模型.造模后药物治疗21 d,取大鼠静脉血.采用ELISA检测血清中IgA、IgG、IgM含量.结果 大鼠血清中3种免疫球蛋白(IgA、IgG、IgM)的含量,妇科千金片高、中、低剂量组分别高于模型组,差异具有统计学意义(P＜0.05);血清IgA的含量,妇科千金片高、中剂量组高于低剂组,差异具有统计学意义(P＜0.05);血清IgM的含量,妇科千金片低剂量组、高剂量组高于中剂量组、妇炎康组、罗红霉素组,差异具有统...

Objective To research the mechanism of Qianjin tablets to treat acute pelvic inflammatory disease.Methods The male Wistar rats were divided randomly into blank group,sham-operation group,model group,fuyankang group,Roxithromycin group,and groups with low,middle and high dosage of Qianjin tablets.After treatment 21 days,the serum content of IgA,IgG and IgM were detected with ELISA.Results The contents of serum IgA,IgG and IgM in mouse in high,middle and low dosage groups were higher than that in model group（P0.05）;the IgA of blood serum in the...